Methodology and early results of the first surveillance program on prevention and control of antimicrobial resistance in Isfahan, Iran: The IAS-I study

Sayed Nasser Mostafavi; Soodabeh Rostami; Behrooz Ataei; Sina Mobasherizadeh; Azam Cheraghi; Somayeh Haghighipour; Samereh Nouri; Arezoo Pourdad; Parisa Ataabadi; Naser Almasi; Leila Heidary; Kourosh Naderi; Setareh Korangbeheshti; Shiva Navabi; Laleh Masssah; Zohreh Norouzi; Mehrnoush Bakhtiyaritabar; Saeed Moayednia; Dariush Shokri; Mahin Mikhak; Majid Rahmani; Mohammad Hashemi; Reza Etminani; Nasrin Ahmadi; Mahboubeh Akhlaghi; Roya Kelishadi

doi:10.4103/ijpvm.IJPVM_189_19

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ORIGINAL ARTICLE

Year : 2020 | Volume : 11 | Issue : 1 | Page : 137

Methodology and early results of the first surveillance program on prevention and control of antimicrobial resistance in Isfahan, Iran: The IAS-I study

Sayed Nasser Mostafavi¹, Soodabeh Rostami², Behrooz Ataei¹, Sina Mobasherizadeh², Azam Cheraghi³, Somayeh Haghighipour¹, Samereh Nouri⁴, Arezoo Pourdad⁵, Parisa Ataabadi⁵, Naser Almasi⁶, Leila Heidary⁶, Kourosh Naderi⁶, Setareh Korangbeheshti⁶, Shiva Navabi⁷, Laleh Masssah⁷, Zohreh Norouzi⁷, Mehrnoush Bakhtiyaritabar⁷, Saeed Moayednia⁴, Dariush Shokri², Mahin Mikhak⁶, Majid Rahmani⁷, Mohammad Hashemi⁸, Reza Etminani³, Nasrin Ahmadi⁹, Mahboubeh Akhlaghi¹⁰, Roya Kelishadi¹¹
¹ Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
² Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
³ Department of Hospitals Supervision and Accreditation, Vice-Chancellery for Clinical Affairs, Isfahan University of Medical Sciences, Isfahan, Iran
⁴ Department of Microbiology, Clinical Laboratory of Alzahra Medical Center, Isfahan, Iran
⁵ Alzahra Medical Center, Isfahan University of Medical Sciences, Isfahan, Iran
⁶ Department of Microbiology, Clinical Laboratory of Dr. Shariati Hospital, Isfahan Social Security Organization, Isfahan, Iran
⁷ Department of Microbiology, Clinical Laboratory of Dr. Gharazi Hospital, Isfahan Social Security Organization, Isfahan, Iran
⁸ Cardiovascular Department, Interventional Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
⁹ Vice-Chancellery for Clinical Affairs, Isfahan Social Security Organization, Isfahan, Iran
¹⁰ Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
¹¹ Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

Correspondence Address:
Soodabeh Rostami
Soffeh Street, Alzahra Hospital, Research Comprehensive Laboratory, Infectious Diseases and Tropical Medicine Research Center, Isfahan
Iran

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/ijpvm.IJPVM_189_19

Background: Isfahan Antibiotic Resistance Surveillance System-1 has been instituted in Isfahan, Iran to construct a project for surveillance of clinically significant bacteria, and to help raise a logic regional stewardship program for prevention and control of disseminating-resistant organisms. Methods: During March 2016 to March 2018, an antibiotic resistance surveillance system was designed and implemented by Isfahan Infectious Diseases and Tropical Medicine Research Center. The surveillance program was implemented in three general hospitals in Isfahan. In addition to the routine microbiology data, clinical data (differentiation between true infections and contamination, healthcare-associated infections (HCAI) and community-acquired infections (CAI), as well as determination of the infection site) were obtained and analyzed by WHONET software. Results: During a 2-year period, from 7056 samples that revealed growth of bacteria, 3632 (51.5%) isolates were detected as contamination and 3424 (48.5%) true bacterial isolates were identified. Of these, about 32% of isolates were recognized as HCAI. Totally, the most recognized infections were urinary tract infection, bloodstream infection and skin and soft tissue infections. In patients with HCAIs, 70% of isolates were gram negative and in patients with CAIs 73% isolates were gram negative bacteria. Conclusions: The strength of the project is gathering enough clinical information in addition to microbiologic data, which would increase application of the results for empiric treatment and prevention of the infectious diseases in clinical settings.

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