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Blood Lead Levels, Hemoglobin, and Liver Enzymes in Opium-Dependent Addicts
Farzaneh Montazerifar1, Mansour Karajibani2, Maryam Lashkaripour3, Manijeh Sayyad Mollashahi4, Abbas Ali Niazi5, Moghgan Soltan Mohammadi6, Samaneh Rahimi Helari6
1 Department of Nutrition, Pregnancy Health Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
2 Department of Nutrition, Health Promotion Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
3 Department of Psychiatric, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
4 Department of Psychiatric, Baharan Psychiatric Hospital, Zahedan University of Medical Sciences, Zahedan, Iran
5 Department of Pathology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
6 Department of Nutrition, Student Scientific Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Correspondence Address:
Farzaneh Montazerifar
Dr. Mansour Karajibani, Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan
Iran
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijpvm.IJPVM_303_18
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Background: Opium addiction, as a major health problem, has been reported in Middle East countries. Recently, contaminated opium has been reported as a probable source of lead poisoning. Thus, the aim of this study is to evaluate blood lead levels (BLL), liver enzymes, and hemoglobin (Hb) concentrations in opium-dependent addicts with healthy controls. Methods: In a cross-sectional study, 75 opium-addicted men (case group) referred to Zahedan Baharan Hospital were evaluated. A group of 75 nonaddicted men were selected as a control group. BLL, Hb, and liver enzymes levels were measured. Body mass index (BMI) was also calculated. Results: The case group had elevated BLL compared to the controls (19.1 ± 1.6 vs. 9.1 ± 0.4; P < 0.0001). Hb concentrations were significantly lower in the patients compared to the controls (13.3 ± 1.6 vs. 15.1 ± 1.3; P < 0.0001). A positive correlation was found between BLL and opium addict duration in the case group (r = 0.52, P < 0.0001). Conclusions: Due to the contamination of opium to lead, it seems that opiate addicts are at risk of lead poisoning. Thus, it is recommended that the blood lead level is frequently monitored to control the adverse effects of poisoning and prevent lead accumulation.
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