• Users Online: 2386
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Browse Articles Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2022  |  Volume : 13  |  Issue : 1  |  Page : 144

Effects of vegetables consumption before carbohydrates on blood glucose and GLP-1 levels among diabetic patients in Indonesia


1 Department of Physiology, Faculty of Medicine; Postgraduate Program of Nutrition Sciences; Biomedical Laboratory, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Jawa Tengah, Indonesia
2 Postgraduate Program of Nutrition Sciences, Universitas Sebelas Maret, Surakarta, Jawa Tengah; Nutrition Installation, Gatot Soebroto Army Hospital, Jakarta, Indonesia
3 Postgraduate Program of Nutrition Sciences; Department of Nutrition Sciences, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Jawa Tengah, Indonesia
4 Biomedical Laboratory, Faculty of Medicine, Universitas Sebelas Maret, Surakarta; Department of Internal Medicine, Faculty of Medicine, Jenderal Soedirman University, Purwokerto, Jawa Tengah, Indonesia
5 Biomedical Laboratory, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Jawa Tengah, Indonesia

Correspondence Address:
Dono Indarto
Jalan Ir. Sutami 36A Kentingan, Jebres, Surakarta 57126, Jawa Tengah
Indonesia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijpvm.IJPVM_704_20

Rights and Permissions

Background: Type 2 Diabetes Mellitus (T2DM) is the prominent public health issue. Pharmacotherapy and diet modification should be integrated into T2DM management. Aims: To investigate the effects of vegetables consumption before carbohydrates on blood glucose and GLP-1 levels in T2DM patients. Methods: A non-randomized quasi experimental study was conducted to recruit T2DM patients who attended at the Gatot Soebroto Central Army Hospital, Jakarta, Indonesia from April to May 2016. The Lemeshow's formula was used to determine sample size. A total of 12 non-diabetic and 24 diabetic patients were participated in our study. Glucose levels were measured using a routine hexokinase method while serum GLP-1 levels were determined using the ELISA. The student t-test was used to compare two groups with parametric data. The significant difference was at P < 0.05. Results: Our data showed that T2DM patients who consumed vegetables before carbohydrates, had relatively stable glucose levels at 0, 60 and 120 mins (164.25 ± 86.89 vs 183.5 ± 55.96 vs 167.83 ± 65.53, P = 0.163) and stay lowered within the normal range compared to T2DM patients who consumed vegetables after carbohydrates (165.08 ± 67.89 vs 241.92 ± 68.03 vs 204.92 ± 81.76, P = 0.022). Additionally, GLP-1 levels remained stable after 60 and 120 min at day 1 (P = 0.816) and day 3 (P = 0.955). Conclusions: Vegetables consumption before carbohydrate is a promising and simple method of diabetes diet for maintaining blood glucose and GLP-1 levels and preventing from vascular complication.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed150    
    Printed4    
    Emailed0    
    PDF Downloaded26    
    Comments [Add]    

Recommend this journal