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Brief Communication:
Assessing the need for routine screening for
Mycoplasma genitalium
in the low-risk female population: A prevalence and co-infection study on women from Croatia
Sunčanica Ljubin-Sternak, Tomislav Meštrović, Branko Kolarić, Neda Jarža-Davila, Tatjana Marijan, Jasmina Vraneš
Int J Prev Med
2017, 8:51 (4 July 2017)
DOI
:10.4103/ijpvm.IJPVM_309_16
PMID
:28757928
Background:
There is an ongoing debate regarding possible cost and benefits, but also harm of universal screening for the emerging sexually transmitted pathogen
Mycoplasma genitalium
.
Methods:
From the initial pool of 8665 samples that were tested, a subset of
Chlamydia trachomatis
-positive and randomly selected
C. trachomatis
-negative cervical swabs were further interrogated for
M. genitalium
by real-time polymerase chain reaction, using a 224 bp long fragment of the glyceraldehyde-3-phosphate dehydrogenase gene.
Results:
M. genitalium
was detected in 4.8% of
C. trachomatis
-positive samples and none of
C. trachomatis
-negative samples. Accordingly, a significant association was shown between
M. genitalium
and
C. trachomatis
(
P
< 0.01), but also between
M. genitalium
and
Mycoplasma hominis
infection (
P
< 0.01).
Conclusions:
Based on the results, routine screening is recommended only for women with one or more identified risk factors. Moreover, younger age does not represent an appropriate inclusion/exclusion criterion for
M. genitalium
testing in the low-risk female population.
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© International Journal of Preventive Medicine | Published by Wolters Kluwer -
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Online since 2
nd
January, 2015