International Journal of Preventive Medicine

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 11  |  Issue : 1  |  Page : 53-

Free radical production in the smoking of e-cigarettes and their possible effects in human health


Roberto Menicagli1, Ortensio Marotta2, Roberta Serra3 
1 Dir Roma Biomed Research Lab, Milan, Italy
2 Prof University Federico II, ENT DEPT Medicine Faculty, Naples, Italy
3 Med Res University, Pavia, Italy

Correspondence Address:
Roberto Menicagli
Roma Biomed Research Lab, Via Martiri Libertà 6a 20060 Mediglia
Italy

Background: The increase in smoking e-cigarettes with nicotine or only flavoring compounds requires a deep study on consequences on human health. This research aims to study the possible process, to form free radicals or the nuclei's damages with consequent micronuclei's formation. Methods: The study analyzed three groups: the first one that uses e-cigarettes with nicotine, (e-nicotine), the second flavoured liquid (e-vapor) and third the not-smoking group. We determinated the salivary malondialdehyde (MDA), the total salivary mucins (SM). and in buccal smear cells the micronuclei (MN). We statistically analyzed the results with the Mann-Whitney U Test Calculator. Results: Smoking e-cigarettes e-nicotine or e-vapor produced a great and significative amount of MDA vs control group: p ≤ 0.05. Only those smoking e-nicotine, have a highest and statically significant amount of salivary mucins vs control group: P value 00496. In both smokers groups, the mean of MN scores has a significant difference vs control group P ≤ 0.05. Conclusions: This study shows the possible damages of the nuclei, but the increase of radicals, oral mucins and MN needs more researches.


How to cite this article:
Menicagli R, Marotta O, Serra R. Free radical production in the smoking of e-cigarettes and their possible effects in human health.Int J Prev Med 2020;11:53-53


How to cite this URL:
Menicagli R, Marotta O, Serra R. Free radical production in the smoking of e-cigarettes and their possible effects in human health. Int J Prev Med [serial online] 2020 [cited 2020 Nov 25 ];11:53-53
Available from: https://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2020;volume=11;issue=1;spage=53;epage=53;aulast=Menicagli;type=0